PUBLICATIONS
-
Crystal structure of dopamine D1 receptor in complex with G protein and a non-catechol agonist.
Sun, B., Feng, D., Chu, M.L., Fish, I., Lovera, S., Sands, Z.A., Kelm, S., Valade, A., Wood, M., Ceska, T., Kobilka, T.S., Lebon, F. and Kobilka, B.K., Nat Commun, 12(1), 3305 (2021) doi 10.1038/s41467-021-23519-9
-
Structural basis for GLP-1 receptor activation by LY3502970, an orally active nonpeptide agonist.
Kawai, T., Sun, B., Yoshino, H. et al. Proc Natl Acad Sci U S A (2020). doi: 10.1073/pnas.2014879117.
-
Structural insights into probe-dependent positive allosterism of the GLP-1 receptor.
Bueno, A.B., Sun, B., Willard, F.S. et al. Nat Chem Biol (2020). https://doi.org/10.1038/s41589-020-0589-7.
-
Structural insights into the activation of metabotropic glutamate receptors.
Koehl A, Hu H, Feng D, Sun B, Zhang Y, Robertson MJ, Chu M, Kobilka TS, Laermans T, Steyaert J, Tarrasch J, Dutta S, Fonseca R, Weis WI, Mathiesen JM, Skiniotis G, Kobilka BK. Nature. 2019 Jan 23. doi: 10.1038/s41586-019-0881-4.
-
Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein.
Zhang Y, Sun B, Feng D, Hu H, Chu M, Qu Q, Tarrasch JT, Li S, Sun Kobilka T, Kobilka BK, Skiniotis G. Nature. 2017 Jun 8;546(7657):248-253. doi: 10.1038/nature22394. Epub 2017 May 24.
-
Crystal structure of the adenosine A2A receptor bound to an antagonist reveals a potential allosteric pocket.
Sun B, Bachhawat P, Chu ML, Wood M, Ceska T, Sands ZA, Mercier J, Lebon F, Kobilka TS, Kobilka BK. Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):2066-2071. doi: 10.1073/pnas.1621423114. Epub 2017 Feb 6.
-
Crystal structures of the M1 and M4 muscarinic acetylcholine receptors.
Thal DM, Sun B, Feng D, Nawaratne V, Leach K, Felder CC, Bures MG, Evans DA, Weis WI, Bachhawat P, Kobilka TS, Sexton PM, Kobilka BK, Christopoulos A. Nature. 2016 Mar 17;531(7594):335-40. doi: 10.1038/nature17188. Epub 2016 Mar 9.